| Specimen Required: |
1. Formalin-fixed, paraffin-embedded (FFPE) tissues from routinely prepared small biopsies are practical and standard for EGFR mutation analysis.
2. Specimens are optimally fixed in 10% neutral-buffered formalin, optimal fixation time ranges from 6 to 24 hours.
3. Presence of tumor cells in the sample must assessed by a pathologist.
4. Ratio of tumor cells to normal cells is crucial for adequate mutation testing and should be provided by the pathologist.
5. One H&E slide and 3-5 unstained slides (6-8 microns ideal) are required for mutation testing. |